Do NSAIDs like ibuprofen cause headaches ?

Posted in Research, Headache, Drug Safety by David Higginson on the June 22nd, 2006

It might seem absurd to question whether the medication that is most widely used to treat headaches can actually cause them.  Researchers set out to answer that question.

A causal relationship between the discontinued use of these medications and decreased frequency of headache has been noticed in patients who have entered headache clinics.
A study published in the medical journal Headache in 2003 concluded that there is a direct relationship between analgesic use and chronic daily headaches, also known as rebound headaches.

Does Chronic Daily Headache Arise De Novo with Regular Use of Analgesics. Headache: The Journal of Head and Face Pain, Volume 43, Number 3, March 2003, pp 179-190 (12)

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